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Zelnorm

Zelnorm (tegaserod maleate) is a drug used in the treatment of irritable bowel syndrome (IBS) and manufactured by Novartis.  It was approved for short-term treatment of constipation in IBS-affected women and for chronic constipation in patients 65 years and younger.  In 2007, Zelnorm was found to cause an increased risk of stroke and heart attacks in patients and Novartis, at the urging of the federal Food and Drug Administration (FDA), withdrew Zelnorm from the market in the United States. 

Fast Facts

Name: Zelnorm
Generic: Tegaserod maleate
Manufacturer: Novartis
Date approved: 2002
Status: Voluntarily withdrawn from market in United States upon request of the federal Food and Drug Administration (FDA)
Approved uses: Short-term treatment of chronic constipation in women with irritable bowel syndrome (IBS); treatment of chronic constipation in patients age 65 and under.
Off-Label uses: Treatment of IBS in men; treatment of idiopathic constipation in patients over 65 years of age
Side effects: Zelnorm has been linked with a higher chance of stroke, heart attack, and chest pain in some patients. Other Zelnorm side effects include abdominal pain, diarrhea and headache.
Related topics: Strattera, Tequin
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Novartis Recalls IBS Drug Zelnorm

It was hailed as a breakthrough treatment for irritable bowel syndrome (IBS) and constipation. Its ad campaign ran prominently on TV and in the national press. But Zelnorm, the IBS drug produced by... read more

Zelnorm Side Effects: Know the Risks

With recent news that Zelnorm, Novartis' "breakthrough" drug for the treatment of IBS (irritable bowel syndrome), has been taken off of store shelves due to safety concerns, you might be... read more

View the Zelnorm Main Articles page here

FDA Information Related to Zelnorm

FDA Permits Restricted Use of Zelnorm for Qualifying Patients

March 2007 Monthly Safety Labeling Changes

View the Zelnorm FDA Information page here

MSN Newsfeeds Related to Zelnorm

Novartis: Latest Victim Of U.S. Economy

Novartis Profit Declines on Lost Sales to Generics (Update10)

View the Zelnorm MSN Newsfeeds page here

News Articles Related to Zelnorm

IntraMed - Art?culos - Complicaciones gastrointestinales de la diabetes

Side-effects study opens up new drug leads

View the Zelnorm News Articles page here

Useful Web Sites Related to Zelnorm

Anapol Schwartz Lawyers - Pennsylvania Zelnorm Lawsuits

View the Zelnorm Useful Web Sites page here

Wikipedia Entries Related to Zelnorm

Tegaserod

Irritable bowel syndrome

View the Zelnorm Wikipedia Entries page here

Books Related to Zelnorm

Guidelines for IBS would streamline diagnostic testing: Zelnorm and Lotronex get 'grade a' status for data showing high efficacy, tolerability. (First ... An article from: Internal Medicine News

New & approved: Zelnorm * Xyrem.: An article from: Internal Medicine News

View the Zelnorm Books page here

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